o:1575 Nova biološki aktivna sintetska azaheterociklična jedinjenja i novi sekundarni metaboliti iz odabranih biljnih vrsta: sinteza, izolovanje i spektralna karakterizacija New biologically active synthetic azaheterocyclic compounds and new secondary metabolites from selected plant species: synthesis, isolation and spectral characterization : doctoral dissertation sr The aim of this PhD thesis was the discovery of new biologically active compounds either by means of natural product isolation from selected plant taxa or by organic synthesis. All of the either isolated or synthesized compounds were characterized by spectroscopic methods, including one- and two-dimensional NMR experiments. The specific compounds that were the subject of this research were: aromatic esters from Ferula ovina (Apiaceae), octyl esters from Heracleum sphondylium (Apiaceae), diesters of an oxygenated germacrane derivative from Daucus carota (Apiaceae), isothiocyanates from Reseda lutea (Resedaceae) and germacrone epoxides from Geranium macrorrhizum (Geraniaceae). Also, as a part of this dissertation, a synthesis of new ferrocene-indole hybrids and the investigation of complex metal hydride reduction of Biginelli compounds was performed. A number of these compounds were tested for their biological activities (antimicrobial, cytotoxic, antinociceptive and antiacetylcholinesterase activities). [O autoru] : Dragan Zlatković: str. [299-301];Bibligrafija: str. 179-189. Datum odbrane: 18.02.2019. Organic chemistry and biochemistry 1025773289 91552101 6699 91552100 1025773289 2019-04-03T19:19:31.053Z 45 no 46 mentor Dragan B. 1984- Zlatković 2018 63 mentor Niko 1981- Radulović 2018 63 član komisije Mirjana 1951- Popsavin 2018 63 član komisije Vidoslav Dekić 2018 63 član komisije Tatjana Ilić-Tomić 2018 63 član komisije Pavle Ranđelović 2018 297 str. 8231908 http://phaidrabg.bg.ac.rs/o:1575 no yes 4 2019-04-03T19:19:31.320Z 70 Organska sinteza, izolovanje prirodnih proizvoda, spektralnakarakterizacija, feroceni, indoli, Biđinelijeva jedinjenja Organic synthesis, natural product isolation, spectral characterization,ferrocenes, indoles, Biginelli compounds 54.057:547.753+547.853.5 615.322:54.061+543.429.23 P 390, P 004 1738 18A07 18A0703 2018