o:1679 Skalabilna softverska platforma za pretraživanje hemijskih i bioloških repozitorijuma A scalable software platform for exploring chemical and biological repositories : doctoral dissertation sr This dissertation is about the SpecINT (Spectral Integration), a scalable software platform, which benefits from the Semantic Web and from the results of spectral graph theory for data integration and exploring semanticbased repositories. In order to save time and resources, institutions are in need of a comprehensive overview of relevant and most recently published data globally. According to statistics, only one substance out of thousands satisfies the preclinical and clinical tests’ criteria and can be used as a medicament. Laboratory conditions require a lot of time and resources to test the effect of large number of substances, and that is why application of in silico models is found necessary. The methodology applied to achieve this goal is based on the coordinates of graph eigenvectors used for automatic join of sub-queries in Federated SPARQL query out of which only the most relevant data sources within repositories are taken into consideration. Such an approach enables reduction of number of duplicates in the results obtained, but also provides useful results for the researchers. In this way the integration of repositories can be effected without a common ontology between them, leaving an impression there exists a searchable central and virtual storage. The platform is developed in collaboration with the Laboratory for Cell and Molecular Biology of the Faculty of Science, University of Kragujevac. However, the methodology can be applied more broadly, since it is based on the „Open Data” standards and concepts. Bibliografija: str. 138-139. Datum odbrane: 12.10.2020. Semantic Web 25058825 91552101 7961 91552100 25058825 2021-03-02T14:43:52.053Z 45 no 46 mentor Branko J. 1984- Arsić 2020 63 mentor Ivan 1965- Milentijević 2020 63 član komisije Dejan Rančić 2020 63 član komisije Leonid Stoimenov 2020 63 član komisije Milorad Tošić 2020 63 član komisije Milan Bašić 2020 XII, 139 srt. 13059397 http://phaidrabg.bg.ac.rs/o:1679 no yes 3 2021-03-02T14:43:52.320Z 70 Integracija repozitorijuma, Semantički Veb, softverskaplatforma, spektralna klasterizacija, teorija grafova Data integration, Semantic Web, software platform, spectral clustering, graphtheory 004.652:[54+57(043.3)004.4:004.659(043.3) P176 1738 18A03 18A0308 2020