http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode https://phaidrani.ni.ac.rs/o:2420 doi:10.2174/1570161118666200518113833 info:eu-repo/semantics/article 2020 eng application/pdf 1892954 bytes Beta-blockers (BBs) are an important class of drugs, with numerous indications in cardiology, emergency and general medicine. The indications include heart failure (HF), acute myocardial infarction (AMI), post-MI , supraventricular and ventricular arrhythmias, chronic coronary syndrome, systemic arterial hypertension (HTN), hypertrophic cardiomyopathy and aortic aneurysm or dissection. All BBs decrease heart rate (HR) and blood pressure (BP), the major determinants of myocardial oxygen consumption; therefore, myocardial anti-ischemic action is a class effect. On the other hand, it is very important that not all BBs decrease all-cause mortality and sudden death; therefore, their crucial characteristics are not the class effect. Current Vascular Pharmacology, Volume 19, Issue 4, pp.343-346 Compelling Indications Should be Listed for Individual Beta-Blockers (Due to Diversity), Not for the Whole Class Koraćević, Goran Koraćević, Maja Stojanović, Milovan Micić, Slađana