o:2420 Compelling Indications Should be Listed for Individual Beta-Blockers (Due to Diversity), Not for the Whole Class en Beta-blockers (BBs) are an important class of drugs, with numerous indications in cardiology, emergency and general medicine. The indications include heart failure (HF), acute myocardial infarction (AMI), post-MI , supraventricular and ventricular arrhythmias, chronic coronary syndrome, systemic arterial hypertension (HTN), hypertrophic cardiomyopathy and aortic aneurysm or dissection. All BBs decrease heart rate (HR) and blood pressure (BP), the major determinants of myocardial oxygen consumption; therefore, myocardial anti-ischemic action is a class effect. On the other hand, it is very important that not all BBs decrease all-cause mortality and sudden death; therefore, their crucial characteristics are not the class effect. Current Vascular Pharmacology, Volume 19, Issue 4, pp.343-346 1552099 10.2174/1570161118666200518113833 2024-03-11T19:29:12.883Z 44 no 46 Goran Koraćević Clinical Center Niš, Department for Cardiovascular Diseases, Obstetrics and Gynecology Clinic, Niš, Serbia + University of Niš, Faculty of Medicine, Niš, Serbia 2020 46 Maja Koraćević Faculty of Medicine, Innovation Center, University of Nis Nis, Serbia 46 Milovan Stojanović Institute for Treatment and Rehabilitation Niska Banja, Nis, Serbia 46 Slađana Micić Faculty of Medicine, University of Nis application/pdf 1892954 https://phaidrani.ni.ac.rs/o:2420 no yes 18 70 92000001 18A15