o:3291 Analiza hemijskog sastava i biološke aktivnosti sekundarnih metabolita biljne vrste Barbarea vulgaris (Brassicaceae) Analysis of the chemical composition and biological activity of Barbarea vulgaris (Brassicaceae) : doctoral dissertation sr The doctoral dissertation is focused on investigating the phytochemicalcomposition of Barbarea vulgaris from Serbia, a member of theBrassicaceae family known for its remarkable intraspecific chemicalvariability. Although this species has previously been the subject ofnumerous studies, populations from our region remain insufficientlydescribed, which highlights the importance of this research within thebroader context of phytochemistry and chemotaxonomy. Specialemphasis is placed on glucosinolates – metabolites essential in plantdefense, recognized as a potential source of pharmaceutically andnutritionally valuable compounds.The research includes the isolation and analysis of essential oil andautolysates of B. vulgaris, identification of glucosinolate degradationproducts, as well as the isolation or synthesis of selected compoundsfor their chemical and biological characterization. Using modernanalytical techniques (GC-FID, GC-MS, NMR, UV-Vis, IR) incombination with biological assays, the antimicrobial, antiinflammatory,and antioxidant properties of the obtained molecules were evaluated.The scientific contribution of this work lies in expanding theknowledge of chemical variability within local populations of B.vulgaris, identifying potentially new chemotypes, and obtainingcompounds that may serve as a basis for the development of newbioactive agents. Biografija: list. 170.Bibliografija: list. 171-172. Datum odbrane: 19.03.2026. Organic chemistry and biochemistry, organic synthesis 91552100 191348745 91552101 8839 2026-06-01T15:47:12.053Z 45 no 46 Amina, Gusinac 88531721 2025 63 član komisije Zoran, 1958- Marković 13598311 2025 63 mentor Milan S., 1980- Dekić 69160201 2025 63 član komisije Marko, 1987- Mladenović 103485961 2025 63 član komisije Мirjana, 1990- Grujović 18316391 2025 63 mentor Ivan, 1974- Palić 14816103 2025 172 listova 10024471 http://phaidrani.ni.ac.rs/o:3291 no yes 12 2026-06-01T15:47:12.320Z 70 organska hemija i biohemija, organske sinteze organic chemistry and biochemistry, organic synthesis 581.192:[582.683.2:577.121](043.3) P 003; P 004; P 300; P 390 1738 18A07 18A0703 2025